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GLA-240 is gamma-linolenic acid (GLA), an "activated" fatty acid found in evening primrose oil and in more concentrated form in borage oil. Extensive scientific research shows that GLA supplementation favorably modulates the body's balance of eicosanoids.
AOR GLA 240 organic gamma linolenic acid 90 softgels
GLA 240 organic gamma linolenic acid - 90 softgels, aor vitamins supplements
on Sale $32.52
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Product is manufactured by AOR Supplements
- Relieves pressure in joints and blood vessels
- Relieves symptoms of premenstrual syndrome
- Reduces symptoms of rheumatoid arthritis
GLA-240 is organic borage oil, a richer
source of the omega-6 essential fatty acid gamma-linolenic acid (GLA),
than evening primrose oil.
|Serving Size: 1 Softgel
|Amount Per Serving
|Gamma linolenic acid (GLA)
|Non-medicinal Ingredients: d-alpha-tocopherol (5 IU). Softgel: gelatin (bovine), glycerin.
that no ingredients not listed on the label have been added to the
product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish
Adult Dosage: Take 1 softgel daily with a fat-containing meal, or as directed by a qualified health consultant.
• Possible interactions with phenothiazines (increasing seizure risk).
• May cause headaches and/or nausea.
• May increase bleeding time.
Pregnancy/Nursing: Consult a qualified health care practitioner
Organic Borage Oil
- Inflammation, swelling and pain
- Pressure in joints, blood vessels
- Water retention
- Allergic response
- Nerve transmission
- Vascular health
first vegetable source of the omega-6 fatty acid gamma-linolenic acid
(GLA) was discovered in the oil of evening primrose seeds (where GLA
content is 9%). This oil became well known with the public, health
professionals, and in health stores. Then GLA was also discovered in
borage and black current in higher amounts, 24% and 17% respectively. A
1992 study published in the journal ‘Lipids’ showed that “there was no
significant difference in tissue GLA levels within groups given equal
amounts of dietary GLA either in borage oil or evening primrose oil”. In
order to ingest 240 mg of GLA, only 1000 mg of 24% borage oil needs to
be taken compared to 2660 mg of EPO. Because reduced consumption of oil
is desirable as a rule, the higher GLA potency of borage oil makes it
preferable to evening primrose oil.
Borage is a plant with star
shaped, periwinkle-blue flowers. The plant produces a dark, rich oil
that contains valuable therapeutic lipids. The seed pod usually contains
about 25% oil content.
body is capable of naturally producing GLA. In order to do this, it
must have its starting material, linoleic acid (LA). This is an
essential fatty acid that the body is unable to make and must be
ingested as part of the everyday diet. Fortunately, most people get
plenty of LA in their daily diet, since it is commonly found in almost
all edible vegetable oils.
Once LA is ingested, it is acted upon
by an enzyme called delta-6-desaturase (D6D) which biochemically
converts LA to GLA. This is how the body gets its daily fix of GLA.
Without the effective functioning of D6D, the body is unable to
manufacture any GLA no matter how much LA is ingested. GLA is further
converted via a sequence of biochemical steps into prostaglandin 1
(PGE1), a key molecule with numerous biological properties including:
• Dermatology (e.g. eczema)
• Nerve transmission
• Secretion from the mucus membrane
• Steroid production and hormone synthesis
rheumatoid arthritis (RA), benefit from non-steroidal anti-inflammatory
drugs (NSAIDs) is mediated through inhibition of the cyclo-oxygenase
enzyme, thereby decreasing production of the 2 series prostaglandins
(PG2). The Lipoxygenase enzyme is intact, however, allowing leukotriene
(LT) production; e.g. LTB4 is an inflammatory mediator. Treatment with
GLA-240 leads to the production of the prostaglandin 1 series PGE1,
which has less inflammatory effects. In addition, LT production is
Post-viral fatigue syndrome
adult patients were treated with GLA for 3 months in a double-blind,
placebo-controlled study. All patients had been ill for 1-3 years of a
viral infection and were suffering from myalgia, severe fatigue and a
variety of psychiatric symptoms. The essential fatty acid composition of
the red cell membrane phospholipid improved significantly.
414 patients with mastalgia were treated with Danazol, bromocriptine,
or GLA. Danazol was the most effective, with GLA and bromocriptine
having equivalent efficacy. However, many more adverse effects were
noted with danazol and bromocriptine.
1 year study observed 111 patients with mild diabetic neuropathy who
were treated with 480mg of GLA per day and assessed for 16 parameters
including tendon reflexes, muscle strength, hot and cold sensation etc.
For all parameters, the changes were more favorable and statistically
significant in the GLA group. The conclusion was that GLA had beneficial
effects on the course of diabetic neuropathy.
fatty acids are supplemented in the diet as they are known to play an
important role in maintaining healthy brain function, for promoting
normal growth and development, and for improving the growth of hair and
skin. They also play an important role in the functioning of the
Evening Primrose Oil (EPO) is the most popular source
of GLA omega-6 fatty acids. However, EPO tends to be very expensive, and
many capsules per day are required to get the full therapeutic amount.
Borage oil is an excellent alternative.
offers an omega-6 fatty acid supplement of the highest quality. AOR’s
GLA-240 is an extract from the seed pods of borage. Borage oil provides a
more concentrated extract of GLA than does Evening Primrose oil,
meaning that fewer capsules are required to get the same effect. It is a
safe and well tolerated supplement that helps regulate inflammation and
reduce the symptoms of a number of disorders.
M, Forleo P, Di Lorio A, Masci S, Abate G, Amerio P. “Efficacy of
gamma-linolenic acid in the treatment of patients with atopic
dermatitis.” J Int Med Res 1997 Sep-Oct; 25(5): 266-74.
KC, Falconer JS, Ross JA, Carter DC, Hunter JO, Reynolds PD, Tuffnell
Q. “An open-label phase I/II dose escalation study of the treatment of
pancreatic cancer using lithium gammalinolenate.” Anticancer Res 1996
Mar-Apr; 16(2): 867-74.
H, Payan J, Allawi J, Walker J, Jamal GA, Weir AI, Henderson LM,
Bissessar EA, Watkins PJ, Sampson M, et al. “Treatment of diabetic
neuropathy with gamma-linolenic acid. The gamma-Linolenic Acid
Multicenter Trial Group.” Diabetes Care 1993 Jan; 16(1): 8-15.
MC, Coetzer H, de Winter R, Gericke G, van Papendorp DH. “Calcium,
gamma-linolenic acid and eicosapentaenoic acid supplementation in senile
osteoporosis.” Aging (Milano) 1998 Oct; 10(5): 385.
J, Makarainen L, Viinikka L, Ylikorkala O. “Biochemical and clinical
effects of treating the premenstrual syndrome with prostaglandin
synthesis precursors.” J Reprod Med 1985 Mar; 30(3): 149-53.
RB, Rossetti RG, Jacobson EW, DeMarco DM, Liu NY, Temming JE, White BM,
Laposata M. “Gamma-Linolenic acid treatment of rheumatoid arthritis. A
randomized, placebo-controlled trial.” Arthritis Rheum 1996 Nov; 39(11):
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