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AOR, Gandha 600, 120 vcaps - Gandha is standardized Withania somnifera (ashwaganha), plant widely used in Ayurveda, the traditional medicine of ancient India. Considered the "Indian Ginseng," ashwagandha is valued for its adaptogenic properties, supporting immune and liver function a
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AOR, Gandha 600, 120 vcaps

AOR Gandha 600 ( ashwaganha ) - 120 vcaps
Gandha 600 ( ashwaganha ) - 120 vcaps, aor vitamins supplements
AOR, Gandha 600, 120 vcaps is manufactured by AOR Supplements

Last updated on 12/5/2016

Gandha-600

  • Supports the function of the immune system and liver
  • Helps with chronic stress and low energy
  • Enhances physical endurance
  • Anti-inflammatory

AOR Gandha-600 is Withania somnifera (ashwagandha), a plant widely used in Ayurveda, the medicine of ancient India. Ashwagandha is traditionally used in Ayurveda as Rasayana (rejuvenative tonic), to relieve general debility, especially during convalescence or old age, as a sleep aid, to balance aggravated Vata (nervine tonic, sedative), and for memory enhancement.

NPN Product Code Size Per Capsule Vegetarian
80023482 AOR04242 120 Vegi-Caps 600 mg Vegetarian
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving

Ashwagandha (Withania somnifera) 10:1* 600 mg

* 2.5% withanolides, 0.1% sitoindosides (typical). Non-medicinal ingredients: Capsule: hypromellose.
Note: Herbal extracts will naturally vary in color from one batch to another.

AOR Guarantees: that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish, shellfish, or any animal byproducts.

Adult Dosage: Take 1 capsule daily, with or without food, or as directed by a qualified health care practitioner.

Cautions: Consumption with alcohol, other drugs or natural health products with sedative properties is not recommended.

Pregnancy/Nursing: Do not use

Source:
Withania somnifera (root)

Main Indications:

  • Stress
  • Edema
  • Support for tense muscles
  • Veta constitutional

Research

Background Information

The King of Adaptogens
If you suffer with chronic stress or flagging energy, then Ayurvedic tradition and a growing body of scientific research suggest that ashwagandha may be worth looking into. Ashwagandha (Withania somnifera), the so-called “Indian ginseng,” is actually not a ginseng species at all; and while it does provide powerful support against overwhelming stress, its effects are in many ways distinct from most other adaptogenic herbs. While most adaptogens primarily work by helping the body to mobilize and maintain the physiological response to stress, ashwagandha appears to work first and foremost by reducing the stress-related excesses of the alarmed nervous system. As science defines these botanicals’ effects and mechanisms of action more precisely, the blanket tag “adaptogen” will no doubt be replaced by a series of more precise terms for substances which help the body adapt to stress in different ways.

Research

Stress and Anxiety
Ashwagandha has traditionally been used as an Ayurvedic remedy for anxiety, an effect well documented in animal models. In a controlled study in humans stressed with repeated, heavy swimming, people taking ashwagandha were better protected against ulcers, depletion of vitamin C, and exhaustion of a key adrenal hormone, and had increased physical endurance compared with people taking Panax ginseng. Similar studies have shown that providing lab animals with ashwagandha leads to better stress tolerance, longer swimming times, greater maintenance of glycogen energy stores, the development of more heart muscle mass, protection against the shrinking of the adrenals and the depletion of vitamin C, and more muscle weight gains.

Likewise, animals experience a great deal of stress when under forced restraint; such animals experience fewer gastric ulcers, less behavioral despair, and less need to pump out natural “pain killers” if given  ashwagandha. As well, ashwagandha protects animals against morphine tolerance, dependence, and toxicity.

Aging
In a double-blind trial in humans, 101 healthy men aged 50 to 59 were evaluated for various aging parameters over the course of a year. Increased red blood cell levels, greater libido, and lower erythrocyte sedimentation rate (a measure of chronic inflammation) were observed in the men who got ashwagandha instead of the dummy pills.

Immunity
Ashwagandha also protects the body against immune suppression. In one study, mice were given one of three drugs that suppress the immune system, with or without ashwagandha added to their diets. Compared with animals receiving the immunosuppressive drugs alone, animals whose diets were supplemented with ashwagandha suffered much less suppression of bone marrow activity, with the result that they had higher hemoglobin, red blood cell count, platelet count, and body weights – and higher levels of the white blood cells of the immune system.

In another study, a mixture of sitoindosides from ashwagandha activated the peritoneal macrophages (a kind of immune cell) in laboratory animals, increasing their mobilization and their ability to consume foreign bacteria while boosting levels of enzymes that help the body break down damaged and toxic molecules left over from the body’s metabolic process. In yet a third study, administration of  ashwagandha extract to either healthy or tumor-bearing animals was found to enhance the proliferation of immune cells and their precursors in the thymus and bone marrow, actually doubling the body’s response to either of two immunological challenges. Ashwagandha also boosted the activity of natural killer (NK) cells, and the immune cells’ ability to destroy infected and foreign cells was enhanced.

Anti-inflammatory
The immune system must ride out a delicate balance, however. So the observation that ashwagandha protects against the suppression of the immune system might lead to concerns that it might overactivate these same processes, potentially aggravating chronic inflammation and autoimmunity. So it’s all the more remarkable that ashwagandha has been found to have significant anti-inflammatory activity, reducing the autoimmune response to an animal model of arthritis to a similar degree as a cortisone drug. In another study, ashwagandha reduced both the degeneration of the joints and the swelling induced by an arthritis-inducing drug in experimental animals.

Chronic Inflammation
In some kinds of chronic inflammation (especially those involving fine particles embedded in the tissue, like silica dust in the lungs or cells infected by fungi or mycobacteria), the chronic attack of immune cells trying to clear the unclearable eventually leads to a nodule made up of densely-packed immune cells trapped within the enlarged local cells. In at least two animal studies, ashwagandha has been shown to reduce the formation of these aggregated cellular nodules (granuloma) after injection with carageenan or implantation with cotton pellets.

A Properly Standardized Extract
The issue of proper standardization of botanicals must always be addressed, to ensure reliable, consistent results for users. The first active compounds discovered in ashwagandha were a family of steroidal lactones collectively called the withanolides. But more recently, a group of glucoside and saponin acyl derivatives of the withanolides – the sitoindosides – were identified. Sitoindosides are more specific markers than the withanolides, and appear to be responsible for much of the herb’s anti-stress and anti-anxiety activities. Accordingly, ashwagandha supplements should be standardized to their sitoindoside content, in addition to their withanolide levels.

Market Trends

With high levels of stress being something that many of us are forced to deal with on a regular basis, it is no wonder that we turn to supplements to help us cope better. There are several herbs and remedies available on the market that are intended to be used as stress relievers. Some of these natural supplements include ginseng, rhodiola, chamomile and others.

AOR Advantage

Ashwagandha is called the “Indian ginseng,” and is actually not a ginseng species at all; and while it does provide powerful support against overwhelming stress, its effects are in many ways distinct from most other adaptogenic herbs. While most adaptogens primarily work by helping the body to mobilize and maintain the physiological response to stress, ashwagandha appears to work first and foremost by reducing the stress-related excesses of the alarmed nervous system.



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