AOR, Estro Adapt, 60 vcaps
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Estro Detox - 60 vcaps, aor vitamins supplements
AOR, Estro Adapt, 60 vcaps is manufactured by AOR Supplements
- Supports liver health
- Promotes detoxification of toxins, carcinogens and excess estrogen
- Reduces the risk of abnormal cellular growth related to excess estrogen in breast and cervical tissues
- Helps balance levels of “bad” and “good” estrogens
- Promotes healthy and regular menstruation
ESTRO ADAPT™ contains hops which are traditionally
used in herbal medicine to help relieve nervousness and choline which
supports liver function.
|NPN (what's this?)
|Serving Size: 2 Capsules
|Amount Per Serving
|LIFENOL® Hops extract† (15-25:1)
|Non-medicinal ingredients: broccoli extract* (300 mg), microcrystalline cellulose, maltodextrin, silica. Capsule: hypromellose. †LIFENOL® is a registered trademark of Naturex, Inc. *Produced under patent US2006/010032 licensed from Caudill Seed Inc.
that no ingredients not listed on the label have been added to the
product. Contains no wheat, gluten, nuts, peanuts, sesame seeds,
sulphites, mustard, dairy, soy, eggs, fish, shellfish or any animal
Adult Dosage: Take 2 capsules daily with breakfast, or as directed by a qualified health care practitioner.
Consult a health care practitioner if you are attempting to conceive,
taking hormone replacement therapy or birth control pills or other
medications, if symptoms persist or worsen, for use beyond 3 weeks, if
you have or are predisposed to cancer or a liver disorder, or develop
liver-related symptoms (e.g. abdominal pain, jaundice), depression
and/or related diseases. Consumption of Hops with alcohol, other
medications and/or natural health products with sedative properties is
not recommended. Some people may experience drowsiness. Exercise caution
if operating heavy machinery, driving a motor vehicle or involved in
activities requiring mental alertness. Discontinue use if you experience
joint pain or hot flashes. Discontinue use and consult a health care
practitioner if you experience irregular menstruation. May temporarily
alter urine colour. Consult a health care practitioner if urine does not
normalize upon discontinued use.
Pregnancy/Nursing: Do not take
LIFENOL® Hops extract; Pharmaceutical synthesis;
- Cellular growth & differentiation
- Women's health
- Liver health
Good vs Bad Estrogens
has long been considered a risk factor for a variety of women’s
cancers, especially breast cancer. In fact, the risk of breast cancer
has been shown to increase with the number of premenopausal years, when
estrogen levels are highest. Research has shown that natural estrogens
can also be classified as “good” or “bad”. For example, 16α-hydroxylated
(“bad”)estrogen metabolites have stronger estrogen activity and are
associated with an increased risk of breast cancer, while 2-hydroxylated
(“good”)estrogen metabolites are weaker and are not associated with
increased risk of estrogen positive cancers.
Estro Adapt to the Rescue
there are natural solutions available that can help tip the balance
towards the “good” estrogens, and to help detoxify and eliminate “bad”
estrogens and xenoestrogens. The ingredients in Estro Adapt work
together to promote a healthy estrogen balance and to promote the
detoxification of harmful substances, thereby helping to reduce the risk
of women’s cancers.
are very important hormones. Although they are present in both men and
women, their best known role is as the primary female sex hormones, and
they are thus involved in the development of female characteristics and
in the regulation of the menstrual cycle. Estrogens have over 400
different functions in the body, some of which include the maintenance
of tissue strength, cardiovascular health, mood, bone health and vision.
Different Types of Estrogen
are many different kinds of estrogens, which can be confusing. The
general term “estrogen” tends to be used to describe all types of
estrogens, including naturally occurring estrogen produced in the body,
estrogens produced by plants (phytoestrogens) and environmental
estrogens (xenoestrogens). What is important to note is that while some
estrogens are healthy and beneficial, other types can have negative
effects. The differences between so-called “good” and “bad” estrogens
have already been discussed briefly. There are also compounds called
xenoestrogens that can have negative biological effects.
For example, xenoestrogens, which are synthetic estrogens encountered
in the environment, are particularly dangerous. These compounds can be
present in synthetic hormones, pesticides and plastics. They do not
react in our body the same way as natural estrogens, and can be
difficult to eliminate from the body. Xenoestrogens have been associated
with disrupted reproductive processes and an increased risk of cancer.
How Do the Ingredients in Estro Adapt Help?
is a naturally occurring compound that is produced by the body in small
amounts and is also found in many fruits and vegetables. D-glucarate
plays a very important role in the detoxification of toxins and
carcinogens. One very important detoxification pathway in the body is
the glucuronidation pathway. Through glucuronidation, toxic substances,
environmental carcinogens and even excess levels of estrogen are
neutralized, and then eliminated from the body.
this important detoxification process can be disrupted by the enzyme
beta-glucuronidase, which reactivates neutralized toxins. Elevated
levels of this enzyme have been associated with an increased incidence
of breast, prostate and colon cancers. This is where D-glucarate comes
in. The primary action of D-glucarate is to inhibit the enzyme
beta-glucuronidase, thereby promoting detoxification. D-Glucarate may
inhibit breast cancer by promoting the excretion of excess estrogen.
is a naturally occurring phytonutrient found in cruciferous vegetables
like broccoli. DIM promotes the formation of 2-hydroxylated estrogen
metabolites instead of 16α-hydroxylated estrogen metabolites. This means
that DIM helps to push the balance of estrogen in the body towards the
production of “good” estrogens and reduces the production of “bad”
estrogens. DIM may also block the activation of genes that promote
cancer cell growth while activating genes that help prevent cancer.
(8PN) is a component found in hops that is a potent phytoestrogen, or
plant estrogen. It has been shown to be of equal or greater potency as
soy-derived phytoestrogens like genistein. 8PN may help reduce breast
cancer cell spreading by interfering with certain pathways mediated by
the estrogen receptor. 8PN has also been shown to prevent angiogensis,
which is the formation of blood vessels that feed tumors.
helps to support liver function and therefore detoxification processes
that are carried out in the liver. Since phase II detoxification takes
place in the liver, choline is an excellent addition to Estro Adapt to
support the detoxification of xenobiotics or excess hormones. Choline is
also an important cofactor for methylation, which is a ubiquitous
process in the body that helps recycle and detoxify various compounds,
including estrogen. Increased choline consumption may also be associated
with a reduced risk of breast cancer.
Sulforaphane (SGS, from Broccoli extract)
is another naturally occurring substance found in the brassica family
of vegetables, such as broccoli. Sulforaphane stimulates the natural
defenses of the body to prevent or improve chronic disease. It is a
natural anti-oxidant and a potent inducer of phase II liver
detoxification enzymes. The phase II detoxification enzymes are
responsible for eliminating harmful toxins and carcinogens from the
has shown that D-glucarate can inhibit breast cancer development in
mice by as much as 70%. Calcium-D-glucarate’s inhibition of
beta-glucuronidase also allows the body to excrete estrogen before it is
reabsorbed by the body. In this way D-glucarate can help to encourage
healthy estrogen metabolism, and prevent elevated estrogen levels.
D-glucarate has been shown to lower serum estrogen levels in rats by
Preliminary studies in humans show that D-Glucarate
supplements are safe, and have the same effects on beta-glucuronidase in
people that they do in animals. Studies on D-glucarate supplements in
women at risk for breast cancer are underway, and it has been suggested
that D-glucarate may provide a safe, effective and side-effect free
alternative to the drug tamoxifen.
cell culture studies DIM has powerful anti-cancer effects, and has been
shown to stop breast and cervical cancer cell growth in vitro. It has
also been shown to block the activation of genes that promote cancer
cell growth while activating genes that help prevent cancer.
studies also show promising results. DIM is currently used to treat
Recurring Respiratory Papillomatosis caused by the Human Papilloma Virus
and is in Phase III clinical trials for Cervical Dysplasia. Cervical
Dysplasia is a precancerous condition also caused by the Human Papilloma
Virus, and is highly correlated to the development of cervical cancer.
Preliminary open-label testing has shown that treatment with DIM
successfully resolved moderate to severe cervical dysplasia.
Research has shown that sulforaphane acts directly to inhibit cancer
cell growth and to initiate apoptosis, or death, of cancer cells through
a variety of mechanisms. In regards to women’s health, sulforaphane has
been shown to inhibit the proliferation of breast cancer cells, and to
reduce their expression of the estrogen receptor, thereby interfering
with the ability of estrogen to bind the receptor and initiate cellular
proliferation and growth.
Hops Extract: 8-prenylnaringenin
vitro, 8PN has been shown to inhibit breast cancer cell proliferation
by interfering with certain pathways mediated by the estrogen receptor.
8PN has also been shown to prevent angiogensis (the formation of new
blood vessels to feed tumors) both in test tube and animal studies.
has benefits for women with menopause. One double blind randomized
cross over study (specifically designed to take into account the high
degree of “placebo” effect common with menopausal studies) showed that
8PN reduced hot flashes, night sweats and other menopausal symptoms
significantly. In animal studies, it has also been shown to help reduce
atherosclerosis and reduce cholesterol levels. It has been proposed that
8PN may help to prevent the incidence of cardiovascular disease
associated with low estrogen levels. Lifenol®’s hops extract is
standardized to contain an effective level of 8PN, and has been studied
in numerous clinical trials.
population-based analysis published in 2008 found that those who
consumed the most choline had the lowest risk for breast cancer. Upon
finding certain genetic polymorphisms, the authors concluded that
choline may reduce cancer cell progression, but the mechanisms are not
imbalances especially among women are a relatively common health
problem. Unfortunately many conventional methods of treating hormonal
imbalances are not always effective or safe.
offers a science backed formula that encourages the balancing of female
hormones, and that helps to support the liver in detoxifying the body
from excess estrogen while also supporting the healthy metabolism of it.
Excess estrogen can have negative results including the development of
hormonal related cancers.
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