AOR, Curcumin-95, 400mg, 90 caps
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Curcumin 95 - 90 vcaps, aor vitamins supplements
AOR, Curcumin-95, 400mg, 90 caps is manufactured by AOR Supplements
- Lowers cholesterol
- Fights bacteria
Curcumin is used in Herbal medicine to help relieve joint inflammation and provides antioxidants for the maintenance of good health.
|| 90 Vegi-Caps
|Serving Size: 1 Capsule
||Amount Per Capsule
| 400 mg
| Non-medicinal ingredients: Capsule: hypromellose.
Note: Herbal extracts will naturally vary in color from one batch to another.
that no ingredients not listed on the label have been added to the
product. Contains no wheat, gluten, nuts, soy, eggs, dairy, fish,
shellfish or any animal byproducts.
Adult Dosage: Take 3 capsules per day, or as directed by a qualified health care practitioner.
Consult a health care practitioner prior to use if you are taking
antiplatelet medication or blood thinners, have gallstones or a bile
duct obstruction, have stomach ulcers or excess stomach acid. Consult a
health care practitioner if symptoms persist or worsen.
Pregnancy/Nursing: Consult a health care practitioner prior to use
Turmeric (Curcuma longa)
- Gastro-intestinal effects
- Cardiovascular effects
- Lipid metabolism
- Anti-tumor activity
is a perennial herb that belongs to the ginger family. The rhizome is
extensively used for imparting color and flavor to food including
curries. As a powder, called turmeric, it is also used for medicinal and
religious ceremonies. Curcumin is an extract of the herb turmeric (Curcuma longa Linn)
which has wide-ranging health benefits. It is well known to have
antioxidant effects, preventing cellular damage, and it reduces the
production of inflammatory signals. It is also able to block the growth
of abnormal cells, stopping cancer before it begins.
A Multi-tasking Supplement
protects the liver from several toxins and regulates lipid metabolism
to decrease cholesterol levels. It protects the gastric mucosa against
irritants. It can fight off many unwanted invaders such as the bacteria Staphylococcus aureus and
various fungal infections, and has even been shown to be a useful ally
against HIV. Curcumin is able to protect the body from damage in a
number of ways. More recently it has been discovered that curcumin is
able to reduce the formation of dangerous amyloid beta plaques in the
brain that are associated with Alzheimer’s disease.
Chemistry of Curcumin
Curcuma longa rhizomes yield about 8% essential oils and 10% fatty oil. Three major constituents have been identified:
(1.) Curcumin (diferuloyl methane)
(2.) Curcumin methane
(3.) Di-hydroxy cinnamoyl methane
volatile oils contain cineol, camphor and linalool and are probably
responsible for the antispasmodic activity. Borneol is present in the
essential oil fraction and is largely responsible for the
digestion-improving properties of curcumin.
Pharmacological Properties of Curcuma longa
The benefits of Curcuma longa have been extensively researched, especially by Indian scientists.
Numerous studies have shown that the various constituents of Curcuma longa
possess potent antioxidant properties. The ability of curcuminoids to
reduce hydroxyl and peroxyl free radicals is well documented. Sharma
reported curcumin to be an effective agent against lipid peroxidation.
The Central Drug Research Institute in India found curcumin to be the
major constituent responsible for the anti-inflammatory activity. The
classical model for studying acute effects of anti-inflammatory agents
is to test their inhibitory action on the development of rat paw edema –
the exudative phase of inflammation – induced, for instance, by the
local injection of carrageenan. Thus inflammation is thought to be in
part due to the action of prostaglandin derivative from arachidonic acid
metabolism. A detailed evaluation of curcumin as a potential
non-steroidal anti-inflammatory agent by Srimal and Dhawan found
curcumin to be highly effective after oral administration. Curcumin was
effective in other models of inflammation including granuloma, pouch,
cotton pellet, formalin-induced, and Freund’s adjuvant.
mechanisms of action have been attributed to curcumin. Some researchers
found curcumin to be less effective in adrenalectomized rats, suggesting
a participation of corticoidal steroids, while others did not observe
any effect of curcumin salts on steroid release from the adrenal cortex.
Recently, another, more specific in-vitro method has been developed
which allows the study of the inhibitory mechanism of potential drugs.
By using rat peritoneal neutrophilis, curcumin was tested for the direct
effect on the 5-lipooxygenase activities. Another study found that
curcumin was able to inhibit the production of pro-inflammatory
mediators in microglial cells that had been stimulated to mount an
inflammatory response. Microglial cells are activated after brain
injuries and produce proinflammatory mediators and neurotoxic compounds.
Curcumin decreased the production of these compounds, apparently by
blocking NF-kB, a protein signal in the pathway that leads to their
production. The overexpression of pro-inflammatory cytokines contributes
to diseases such as Alzheimer’s, cerebral ischemia and many
degenerative and inflammatory conditions. The ability of curcumin to
decrease inflammation presents an approach to slow the progression of
3. Gastro-intestinal effects
increases mucin content, thereby protecting the gastric mucosa against
irritants. Controversial data exist regarding an anti-ulcerogenic
activity of curcumin. Some researchers found a protective effect of
curcumin against histamine-induced gastric ulceration, while others
reported an ulcerogenic effect of curcumin.
possesses anti-spasmodic properties. Curcumin showed liver protective
effects against carbon tetrachloride, D-Galactosamine and peroxide
induced cytotoxicity. Curcumin increased bile acid production in dogs
4. Cardiovascular effects
A sharp and transient
hypotensive effect of curcumin was reported in dogs. Curcumin also
inhibited collagen and adrenaline-induced aggregation of platelets but
did not affect prostacyclin (PGI2) synthesis.
5. Lipid metabolism
Rao and co-workers reported that rats fed with curcumin and cholesterol
in their diet had only half to one-third of the serum and liver
cholesterol levels compared to the controlled groups receiving
Curcumin inhibited growth of most organisms including: Staph aureus, Streptococci, Lactobacilli, Corynebacterium, Baccilus aureus, and Micrococcus pyogenes. The crude ether and chloroform extracts of Curcuma longa showed fungistatic activity against several dermatophytes as well as anti-amoebic activity against Entamoeba histolytica.
A 1993 study showed curcumin as an effective ally in the treatment
against HIV. Curcumin was effective in inhibiting the replication of HIV
in both acutely infected and chronically infected cells.
8. Anti-tumor activity
The anti-tumor activity of various extracts of Curcuma longa
has been remarked by several researchers. Topical application of
curcumin inhibited the number of TPA-induced tumors by as much as 98%!!
Curcumin was found to be a selective and non-competitive inhibitor of
products have a longstanding reputation for being beneficial in the
treatment and prevention of a variety of ailments. It is a substance
that is considered very safe to use and that offers multiple health
benefits. However, curcumin is the active ingredient in turmeric
responsible for these effects, and it is the compound with which most of
the clinical studies have been conducted, not turmeric.
offers a standardized and potent curcumin extract, not a weak turmeric
extract, that provides antioxidant, anticancer, anti-inflammatory,
cholesterol lowering, anti-tumor and antimicrobial benefits.
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