AOR UTI Cleanse Now with Cranberry helps prevent recurrent urinary tract infections (UTIs) and is a source of antioxidants for the maintenance of good health..
| NPN
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Product Code
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Size
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Per Capsule
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Vegetarian
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| 80024732
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AOR04252
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60 Tablets
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700 mg
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100% Vegetarian
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| 80024732
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AOR04251
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120 Tablets
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700 mg
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100% Vegetarian
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| Supplement Facts
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| Serving Size: 1 Tablet
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Amount Per Tablet
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| Cranberry Extract
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200mg
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| D-Mannose
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500mg
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Non-medicinal ingredients: Microcrystalline cellulose, carboxymethylcellulose sodium, sodium stearyl fumarate, and silicon dioxide.
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AOR guarantees that no ingredients not listed on the
label have been added to the product. Contains no wheat, gluten, corn,
nuts, dairy, soy, eggs, fish, shellfish or any animal byproduct.
Suggested Use:
Take 2 tablets daily without food,
or as directed by a qualified health care practitioner. Use for a
minimum of 4 weeks to see beneficial effects.
Main Applications
Urinary tract infections
Source
Cranberry, Norwegian birch tree bark
Pregnancy / Nursing
No studies have been conducted, but believed safe. Consult with a physician.
Cautions
Consult
a health care practitioner prior to use if you are taking blood
thinners or have a history of kidney stones. Consult a health care
practitioner if symptoms persist or worsen.
What Causes Urinary Tract Infections?
Although urinary tract infections (UTIs) can involve a variety of
different bacteria species (including Staphylococcus saprophyticus and
some enterococci species), nearly all infections of the lower urinary
tract and bladder are caused by a few strains of E. coli bacteria called
uropathogenic Escherichia coli (UPEC). Various harmless strains of E.
coli are normally present in the body - but they don't belong in the
urinary tract.
If UPEC get into the bladder or the urethra, the body has ways of
fighting them off - including the obvious method of simply flushing them
out with the urine. But these bacteria have evolved ways of anchoring
themselves to the cells of the urinary tract. The invading UPEC take
advantage of receptors naturally found on the cells of the mucosal
lining of the urinary tract. Receptors are like molecular "docking bays"
for substances that the cells need for their normal growth and
development. Like pirates in an old movie, UPEC use "grappling hooks"
called type I pili to first hook on to these receptors, and then to
invade the cell.
Once inside the cell, these pathogens can live and reproduce in
safety, shielded from many of the body's defensive immune responses. In
fact, they are so sophisticated that when the body detects that cells
have been infected and activates the cell suicide program to destroy the
bacteria, UPEC can actually flee the dying host cell before it is
flushed out, and look for new cells to invade!
The Role of D-Mannose in the prevention and Treatment of UTI’s
Pathogenic E. coli bacteria's pili "grappling hooks" are composed of
long, fibrous chains of molecular "glue" called adhesin. The effective
binding of these adhesin molecules depends on the chemical attraction
that exists between them and the residues of a simple carbohydrate
called D-Mannose on the cell surface receptors of the urinary tract host
cells.
The chemical attraction between UPEC adhesins and D-Mannose is their
strength - but it also provides a point of vulnerability. If you can
interfere with the binding of adhesins to the D-Mannose residues in the
receptors of your urinary tract cells, then you can also prevent UPEC
from getting a foothold for adherence and infection. One way to do this,
long known to work in a test tube, is by using D-Mannose itself. When
isolated urinary tract cells are bathed in D-Mannose, it acts as
molecular "chaff." The bacterial adhesins bind to the D-Mannose in their
environment instead of to the D-Mannose residues on the cells. This
gums up their pili and prevents them from hooking onto urinary tract
cells.
It was discovered in the late 1980s that a small amount of D-Mannose
is present in the urine normally, apparently acting as a defensive
mechanism against pathogenic bacteria. When D-Mannose is taken as a
supplement, much more of the carbohydrate passes through the urinary
tract, strengthening this natural defense.
A decade after this discovery, Dr. Jonathan V. Wright of the Tahoma
Clinic pioneered the use of D-Mannose supplements to fight off UTIs. For
some years, he has been reporting the successful results that his
patients have experienced in using D-Mannose to rid themselves of
infection. Even patients who had remained infected after having been
subjected to a wide range of potent, side-effect-inducing antibiotics
have successfully rid themselves of chronic or acute infections using
D-Mannose. Other nutritionally oriented physicians and health
practitioners have since adopted Dr. Wright's protocols, and the
feedback is uniformly excellent from UTI sufferers and their caregivers
alike.
Again, not all UTIs are caused by UPEC. So if you try a course of
D-Mannose and infection persists, it is likely not caused by these E.
coli bacteria but by some other pathogen. In that case, don't just keep
going on with the supplement in hopes that it will eventually "kick in:"
discontinue use of D-Mannose and consult a physician for treatment
appropriate to your case. But for the great majority of urinary tract
infections, D-Mannose offers a safe, natural option with a simple,
ingenious rationale, no known side-effects, and a great reported success
rate.
Cranberry Extract for an Enhanced Effect
Cranberries have been used in the treatment of UTI for many years and
are now regarded as a non-pharmaceutical approach for the treatment and
prevention of simple UTI infections. Like D-Mannose, cranberries are
effective in the treatment of the majority of UTI caused by by E.coli.
Cranberries and cranberry extracts acidify the
urine, which reduces bacterial growth. Furthermore, cranberries also
contain certain tannins called proanthocyanidins that have been shown to
reduce bacterial adherence to the urinary tract wall. It has been shown
that within 3 hours after ingesting cranberry, molecular changes in the
adhesion apparatus used by bacteria to attach themselves to the urinary
tract wall occur. This is a significant benefit in the treatment of
UTIs as adherence is essential for infection.
If bacteria cannot attach themselves to the urinary tract wall, they
cannot cause an infection. However, once attached to the urinary tract
wall, bacteria cannot be removed by the body's normal clearing
mechanisms. Studies have documented that drinking eight glasses of
cranberry juice twice a day can eradicate most UTIs. If consumption is
maintained, infection is unlikely to recur; a Harvard study has
demonstrated that regular use of cranberry juice reduced bacterial
growth in the urinary tract. Studies have demonstrated that infections
can be reduced by over 50% in elderly women drinking 300 ml of cranberry
juice per day. In general, cranberry tablets are more cost effective
than cranberry juice in the treatment and prevention of UTI. UTI Cleanse
Now with Cranberry contains a concentrated extract, the 400mg daily
dose of this extract is equivalent to roughly 1 cup of cranberries.
A Superior Combination
UTI Cleanse Now with Cranberry combines two ingredients that are well
known and highly effective for the natural prevention and treatment of
UTI’s, namely D-Mannose and Cranberry Extract. This superior and
convenient combination provides a one-two punch for individuals battling
recurrent urinary tract infections.
SKU Number: AOR04251
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: AOR04251