AOR, Cardio Mag 2.0, 770mg, 120 caps
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Cardio Mag 2.0 - 120 vcaps, aor vitamins supplements
AOR, Cardio Mag 2.0, 770mg, 120 caps is manufactured by AOR Supplements
Cardio Mag 2.0
- Helps the heart deal with and recover from stress
- Increases heart energy stores and energy production
- Clinically shown to help patients with cardiac disorders
Cardio Mag 2.0 is true magnesium orotate. Magnesium
and orotic acid exert complementary effects on the biosynthesis of
pyrimidine nucleotides, supporting the heart's ability to endure and
recover from chronic and acute stressors through the maintenance of
normal glycogen stores, protein synthesis, ATP levels, and contractile
function. Research supports the ability of true magnesium orotate to
support cardiac function. The magnesium orotate in AOR's CardioMag 2.0
is fully-reacted, unlike most "magnesium orotate" products which are
food-grade mixtures of orotic acid with inorganic magnesium salts.
|Serving Size: 1 Capsule
|Amount Per Serving
|Non-medicinal ingredients: silicon dioxide. Capsule: hypromellose, water.
that no ingredients not listed on the label have been added to the
product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish,
shellfish or any animal byproduct.
Adult Dosage: Take 4 capsules daily, or as directed by a qualified health care practitioner.
Cautions: None known
Pregnancy/Nursing: Consult a qualified health care practitioner prior to use.
- Supports cardiac function
- Supports healthy blood pressure balance
True Magnesium Orotate for Cardiovascular Health
health-conscious people about the mineral most important to their heart
health, and most will hit on magnesium right away. But few people look
beyond the amount of elemental magnesium in their supplements to
consider the importance of the other half of their magnesium supplement –
the chelating amino acid or anion to which it’s bound. For instance,
the widely-used magnesium oxide has “extremely low” bioavailability
(22.8%), making it more likely to cause diarrhea; and on top of this
embarrassing side-effect, magnesium oxide is an antacid, which can
impair digestion and nutrient absorption. But there’s more to the
effects of a magnesium supplement than its bioavailability. Because the
“other half” of one magnesium supplement is extensively documented to
have profound effects on cardiovascular health. That supplement is true,
fully-reacted Magnesium Orotate.
Orotate is magnesium bound to orotic acid, a key intermediate in the
biosynthesis of pyrimidine nucleotides (a building block of the
“letters” of your DNA code, and of RNA, the messenger that delivers the
instructions from the DNA to the cellular machinery that assembles
cellular proteins based on DNA’s commands). Although little known and
underappreciated, decades of research and clinical trials have
documented the powerful benefits of Magnesium Orotate to the weakened
The use of orotic
acid and its mineral forms as metabolic therapy for cardiovascular
patients began in the early 1960s in the former Soviet Union, where it
was primarily used to provide support to patients with heart failure,
particularly in cases of cardiomyopathy. Animal models had shown that
heart failure increases the demand for RNA for the biosynthesis of
proteins needed to repair the heart. So Soviet cardiologists reasoned
that, since orotate is needed for biosynthesis of RNA precursors,
supplemental orotate might speed the recovery of heart muscle function.
models provided early evidence to support the Russian scientists’
expectations, showing that supplemental orotate increases cardiac
glycogen, protein synthesis, and ATP levels (all depressed by infarction
or heart failure), and improves cardiac contractile function following
damage to the heart, without interfering with normal baseline function
in healthy hearts. This evidence was enough to get Russian cardiologists
going on clinical trials of mineral orotates in the 1960s, which
clearly showed the benefits of orotate supplementation.
Magnesium Orotate: the Synergistic Cardiovascular Supplement
the early days, research was conducted on a variety of mineral
orotates, such as calcium orotate and potassium orotate. It was only
later that researchers picked up on the unique advantage of combining
orotate with magnesium to create one unique cardiovascular health
supplement: Magnesium Orotate. This combination not only takes advantage
of magnesium as a heart-health supplement in its own right: the
magnesium in Magnesium Orotate is a key cofactor for the very enzyme
that uses orotate to biosynthesize the RNA precursors (pyrimidine
nucleotides) through which orotate strengthens and restores heart cells
A Remarkable Safety Record
Orotate has been documented to be an extremely safe supplement. A 1998
review of studies on Magnesium Orotate states that “No adverse effects
arising from [orotic acid] administration in humans have been reported”.
Even diarrhea – the most commonly-reported side effect of magnesium
supplements – appears to be extremely rare in Magnesium Orotate users:
there has only been one trial of Magnesium Orotate reporting any
diarrhea, and this was unusual and did not lead to anyone quitting their
Magnesium Orotate use.
While animal experiments once suggested
that high-dose orotate supplements might harm the liver, this turned out
to be a quirk of the unusual metabolism of the rat, which doesn’t apply
in other species. Quite the contrary, in fact: orotate and its salts
have been used as a treatment for a variety of liver disorders in
Probably the best evidence of the safety of high-dose
orotate supplements are the many trials in which they have been safely
used without side effects in vulnerable population groups, such as
children with hypertension or liver and bile duct disorders, as well as
pregnant women and even infants with jaundice.
Not Just Another Magnesium
all of the decades of research backing the benefits of Magnesium
Orotate, why is it not more widely available? In part, it’s because the
research is so new to the West. And if you don’t know about the specific
benefits of the orotic acid that’s so critical to the actions of a
Magnesium Orotate supplement, and think that the heart-health benefits
of a magnesium supplement come entirely from the magnesium itself, then
you might easily think that Magnesium Orotate is “just another magnesium
supplement” on a shelf full of other, cheaper, and lower-pill-count
Also, Magnesium Orotate is a bulky supplement. The
orotic acid ligand in Magnesium Orotate is a big molecule, so when
magnesium is bound to it, the final complex is only about 6.5% elemental
magnesium by weight. But to compare Magnesium Orotate to other
magnesium supplements on a simple milligram-for-milligram basis is
misleading, because Magnesium Orotate is not just a magnesium
supplement: its cardiovascular benefit derives from the orotic acid as
much as it does from the magnesium itself. And you don’t need a whole
RDA’s worth of elemental magnesium to enjoy its effects: the many
clinical trials on Magnesium Orotate clearly document that the
cardiovascular benefits from Magnesium Orotate are achieved at doses of
200 mg of elemental magnesium or less.
A True Chelate
you know about the superior cardiovascular benefits of Magnesium
Orotate, however, you still have the problem of locating the real thing.
The fact is that the great majority of the “Magnesium Orotate” on the
market is not pure, fully-reacted Magnesium Orotate, but a “blend” or
“complex,” mostly made up of magnesium oxide. These products look
attractive, because they claim to provide this desirable form of the
mineral, yet are cheap and contain a high amount of elemental magnesium
per tablet – but that’s only because the Magnesium Orotate in these
supplements is “cut” with cheaper, denser forms of the mineral.
be sure that you’re getting the real thing, compare the amount of
elemental magnesium listed on the label with the amount of orotic acid.
True, fully-reacted Magnesium Orotate contains nearly 15 times as much
orotic acid as magnesium by weight. If the label isn’t clear on this
point, you can’t be sure of what you’re getting. Then, be prepared for
the small added cost of genuine Magnesium Orotate, and the need to fit
an extra capsule or two into your pill box. These minor inconveniences
will pay major dividends in the health of your heart.
Magnesium Orotate is a supplement with solid, proven benefits in
supporting the health of the heart and in restoring performance and
quality of life in people whose hearts have been challenged. If you – or
someone you love – have a history of, or a risk for, a stay in a real
“Heartbreak Hotel,” you owe it to yourself to look seriously into this
powerful nutritional combination.
Trials Confirm the Power of Magnesium Orotate
Congestive Heart Failure
and coworkers performed a randomized, controlled trial in 32 congestive
heart patients who had recently undergone coronary artery bypass
grafting (CABG) surgery. Within two days of surgery, each participant
received either a 2000 mg Magnesium Orotate supplement or a placebo
dummy pill as an add-on to their standard heart medication. Eight weeks
later, Magnesium Orotate users experienced functional improvements on a
wide range of heart function parameters in comparison with those taking
the placebo, including exercise times, angina-free walking distance, and
VO2max; most notably, they enjoyed a 63% lower risk of suffering extra
systoles (“extra” heartbeats, felt as “missed” beats or “flip-flops” in
Mitral Valve Prolapse
second controlled trial compared the effects of 3000 mg Magnesium
Orotate with standard control treatment in 84 people suffering with
mitral valve prolapse. The results: a “6-month therapy with [Magnesium
Orotate] completely or partially reduced the symptoms in more than half
the patients. Positive changes were registered primarily in
Coronary Heart Disease and Left Ventricular Dysfunction
a third study, fourteen coronary heart disease patients with left
ventricular dysfunction who were undergoing an exercise therapy program,
took either Magnesium Orotate (3000 mg) or placebo pills as an add-on
to their existing medications for four weeks. Compared with the placebo
group, users of Magnesium Orotate enjoyed greater improvements in
exercise times and in the emptying and filling of the left ventricle.
the most recent study, Magnesium Orotate was used as a central part of a
“Metabolic Physical and Mental (MPM) Program,” a whole-lifestyle
intervention involving an exercise (Physical) component, stress
reduction (Mental), and Metabolic supplement use (1200 mg Magnesium
Orotate along with coenzyme Q10, lipoic acid, and omega-3 fatty acids).
In this historically-controlled trial, the MPM program was compared to
previous cases given standard care in 11 elderly people scheduled for
cardiac surgery. Even in the two week period between starting the trial
and going under the knife, Magnesium Orotate users undergoing the MPM
improved their overall quality of life. And one month after surgery the
benefits became striking. As part of the MPM, using Magnesium Orotate
led to a full 50% jump in physical quality of life, while mental quality
of life also got 24% better. By contrast, scores on all of these
parameters had gotten worse during the same periods in the historical
control group. Meanwhile, malondialdehyde (a marker of lipid
peroxidation and thus of free radical stress) plunged 45%.
Angina, Child Hypertensives and Arterioslcerosis
clinical trials have documented the effectiveness of Magnesium Orotate
supplements in delivering improved quality of life in elderly patients
with stable angina; in supporting exercise and a salt-restricted diet to
reduce blood pressure, eliminate heart palpitations, and improve sleep
quality in child hypertensives; and in improving the flexibility of
blood vessels and reducing anginal pains in patients with
arteriosclerosis or inflammatory vessel disorders.
a recent double-blind, randomized controlled trial, Magnesium Orotate
supplementation has also been found to simultaneously improve physical
performance, and reduce some of the punishing negative impacts of
extreme physical exercise, in triathletes.
supplement with magnesium alone in an effort to improve their health.
Those wishing to improve their heart function and overall health would
benefit not only from a magnesium supplement but from a magnesium
Mag 2.0 is a fully reacted and pure form of magnesium orotate which
provides significantly higher levels of orotic acid than many other
supplements on the market.
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