AOR Bone Basicsis a multi-nutrient combination designed to support bone health. It features a
hydroxyapatite complex
(MCHC), an extract of bovine bone derived from Australian pasture-fed, free-range livestock not subjected to routine antibiotics or rBGH. Calcium intake, when combined with sufficient vitamin D, a healthy diet, and regular exercise, may reduce the risk of developing osteoporosis.
360 Capsules AOR04231
SUPPLEMENT FACTS:
Serving Size: 6 Capsules
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*Dietary Reference Intake not established.
Other ingredients: ~0.06% sucrose, <0.05% starch, <0.04%
gum Arabic, <0.03% acacia, ~0.02% coconut oil, calcium phosphate, ~
0.0002% dl-alpha tocopherol. Capsule: hypromellose, sorbitol, silicon
dioxide, water.
AOR guarantees that no ingredients not listed on the label have been added to Bone Basics. Contains no wheat, gluten, nuts, dairy or eggs.
Suggested Use
Take up to six capsules daily, dividing the dose among meals to
facilitate maximum absorption, taking the largest single dose with the
last meal or snack of the day, or as directed by a qualified health
practitioner.
Main Applications
As reported by literature:
Excellent source of calcium and other nutrients.
Bone health.
Source
MCHC: lyophilized, defatted bone tissue from free-range,
pasture-fed Australian bovine livestock not subjected to routine
antibiotics or rBGH. Guaranteed free of bovine spongiform
encephalopathy.
Pregnancy / Nursing
Safe.
Cautions
None known.
Complementary Products
CS/G
MSM+GLS
Peak K2
Strontium Support
*These statements have not been evaluated by the Food and
Drug Administration. This product is not intended to diagnose, treat,
cure, or prevent any disease.
The information and product descriptions appearing on
this website are for information purposes only, and are not intended to
provide medical advice to individuals. Consult with your physician if
you have any health concerns, and before initiating any new diet,
exercise, supplement, or other lifestyle changes. Any reproduction in
whole or part and in print or electronic form without express permission
is strictly forbidden. Permission to reproduce selected material may be
granted by contacting AOR Inc.
Copyright 2005, Advanced Orthomolecular Research
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Changes in posture and gait are as universally associated with
aging as changes in the skin and hair. Posture and gait are centered on
the health of the 206 bones that comprise the human skeleton. These
bones do not directly contact each other as they are connected (and
cushioned) by the cartilage, membranes, and fluid that comprise the
joints.
As people age, bone mass and/or density is gradually
lost, especially in women after menopause. The bones lose calcium,
magnesium and other minerals, making the bones thinner in a process
referred to as osteopenia. Osteopenia, over time and further bone loss,
leads to full-blown osteoporosis. Minerals such as calcium are
constantly being added to and taken away from bone. When these minerals
are taken away faster than they can be added, (a process that
accelerates with age) the bones become lighter, less dense, and more
porous. This makes the bones weaker and increases their risk of
fracture.
Bone Mineral Density (BMD) tests can measure the extent of
this process with regular x-rays, but such tests cannot measure any mild
onset of osteopenia. In fact, a bone must lose at least a quarter of
its weight before a regular X-ray can detect the problem.
Maintaining Bone health: a one-a-day may not cover it
The
thicker the bones are, the less likely a person is to suffer a fracture
and the longer it takes to develop osteopenia and later osteoporosis.
This is the most plausible explanation why post-menopausal women
comprise 80% of osteoporosis sufferers. Maintaining a high level of Bone
Mineral Density (BMD) is therefore a point of order for this
demographic, not to mention anyone else for whom bone health is a
concern.
Traditional methods of maintaining bone health correlate with the
efforts of health conscious individuals who supplement with a daily
multi-vitamin/multi-mineral. Users of such an essential supplement
(combined with a sensible diet) often assume that it covers something as
elemental as bone health. The fact of the matter is that people in the
high-risk demographic for developing osteopenia likely have a higher
need for certain specific essential nutrients, especially minerals. Of
these, calcium is certainly one of the most familiar. Most recommended
daily allowances for calcium stand at around 1,000 milligrams, although
1,500 milligrams are recommended for those in the osteopenia high risk
group. Even with the effects of processing taken into account, calcium
is still prevalent to such a degree in common dairy foods such as milk
and cheese that deficiencies are not as widespread as that of other
minerals. Nevertheless, deficiencies do occur, and it is noteworthy to
remember that even the finest multi-vitamin/multi-mineral one-a-days
rarely contain more than 300 milligrams of calcium.
Another nutrient essential to bone health is vitamin D. Vitamin D is
the single most important factor in the absorption of calcium. A
superior form of vitamin D is vitamin D3 (also known as
cholecalciferol), a colorless crystalline compound found in fish-liver
oils. Research has shown that cholecalciferol is the preferred, active
form of vitamin D in the body. Although humans are fully capable of
endogenous vitamin D production, this is dependent upon adequate
exposure to the UVB rays in sunlight, making a constant, steady intake
of this vitamin difficult for high-risk demographics who are often
confined indoors. This is compounded by the lack of sunlight in the
winter months and in more extreme latitudes, further underlying the
importance of supplementation. Clinical trials show that calcium
supplementation provides better results when combined with vitamin D at
doses greater than 300 IU per day.
Magnesium is another mineral commonly associated with the maintenance
of bone health, which is very easy to fathom when one considers that
two-thirds of the body's magnesium stores are located in our bone
structure. Much of the magnesium within this bone structure is part of
the bone's crystal lattice (which can metaphorically be referred to as
the "bone scaffolding") where it binds together with the minerals
phosphorus and calcium. Magnesium on its own has been shown to slow the
rate of bone turnover, which is when the growth of new bone is outpaced
by the degeneration of old. Magnesium shortages result in the reduced
assimilation of Vitamin D as well as the inhibition of parathyroid
hormone, leading to low blood calcium levels. Magnesium also seems to
work synergistically with MCHC (see below) by helping to form smaller,
denser, microcrystalline hydroxyapatite crystals, providing yet another
avenue for strong bone development. In a two-year, open, controlled
trial, 71% of women receiving magnesium supplements experienced
increased bone mineral density where as the women not receiving
supplements suffered bone loss. The amount of magnesium in even the
highest quality multi-vitamin/multi-mineral supplements is still well
below levels which researchers believe are needed for prevention in high
risk demographics.
Several other minerals have also been identified as co-factors for
enzymes involved in bone metabolism - notably zinc, copper, and
manganese. The latter is essential for the proper function of the
osteoblast cells that are responsible for building new bone. Manganese
also increases the activity of the enzyme alkaline phosphatase and as
well as growth factors such as estrogen and IGF-1 in a manner that is
directly pertinent to these osteoblast cells. Copper is essential for
producing an enzyme called lysyl oxidase which cross-links (strengthens)
collagen. Zinc, in turn, is essential for the operation of copper,
since unbalanced zinc intake can reduce copper absorption.
There are also certain nutrients that are especially noted for their
effects on bone integrity. These include Ossein Microcrystalline
Hydroxyapatite Complex (MCHC) and glucosamine hydrochloride (HCI). MCHC
is a freeze-dried extract of bovine bone, and this process of
lyophilization is important in retaining the intact microcrystalline
structure of whole bone. This is a significant differentiation from
regular bonemeal, which uses a heat-treated process called "ashing".
Many of the unique bone-building factors of MCHC are heat-sensitive and
simply do not survive this process, and this has been demonstrated in
clinical studies comparing MCHC directly to bonemeal. Furthermore, the
ideal source for MCHC would be pasture-fed, free-range livestock not
subjected to routine antibiotics or recombinant bovine growth hormone
(rBGH). This would not only insure that the widest possible range of
micronutrients within the whole bone extract would survive the
manufacturing process, but it would also provide assurances against
bovine spongiform encephalopathy, commonly referred to as mad cow
disease. The most reputable sources of such livestock appear to be from
Australian, New Zealand and Argentine pastures, where local legislation
and/or custom either prohibits, limits or discourages routine
antibiotics and recombinant bovine growth hormone (rBGH). MCHC is, in
effect, a full-spectrum multiple nutrient source in its own right.
However, it is particularly rich in calcium, and the type of calcium in
MCHC has been clinically proven in over 30 years of randomized,
double-blind, controlled clinical trials to be the best calcium source
for bone building and maintenance. Other calcium sources such as calcium
gluconate, calcium citrate, calcium carbonate, calcium citrate-malate
and even coral calcium (which in fact is simply calcium carbonate with a
sprinkling of trace minerals) may be capable of slowing down the rate
of bone loss. MCHC, in contrast, has actually been proven to halt and
even reverse bone loss attributable to osteoporosis.
Glucosamine is an aminomonosaccharide, meaning that it is the product
of a synthesis between glucose and an amino acid -in this case
glutamine. Glucosamine is produced naturally in the body by chondrocytes
in cartilage to help maintain and build healthy joint tissue. The main
basic purpose of Glucosamine is to create long chains of modified
disaccharides called glycosaminoglycans (GAGs), which the joints and
cartilage require for repair. The GAGs are the main component of
proteoglycans (PGs), which along with chondrocytes and collagen, make up
cartilage. Glucosamine is also converted in the body to
N-acetyl-glucosamine, which in turn is critical to the formation of
hyaluronic acid. Hyaluronic acid is the central component of synovial
fluid which acts as a lubricant in the joints.
Precedent
In 2005 AOR established a strong
precedent in the field of preventative bone health with the introduction
of a product called Calcium Magnesium Plus®. This product was
exceptionally well received by health professionals and consumers alike.
In keeping with AOR's policy of distinction via innovation, Bone Basics
was developed as a new and improved successor to this original product. AOR Bone Basics is a complete bone health formula, including calcium,
magnesium and many other key nutrients to help support the maintenance
of healthy bones. The formula also includes Vitamin K as menatetrenone.
Menatetrenone (MK-4) is a form of Vitamin K2 that is naturally produced
by the body from Vitamin K1. Recent studies have suggested that vitamin
K2 is better absorbed and persists longer in the plasma then vitamin K1.
Studies have also shown that it also has greater benefits to the
skeletal and vascular systems than vitamin K1. Vitamin K is important
for bone health as it is able to regulate calcium through the amino acid
gamma-carboxyglutamic acid (Gla), and in particular the protein
osteocalcin, which helps maintain calcium in bone, but at the same time
keeps it out of soft tissue.
Another ingredient included in Bone
Basics is Boron, a mineral that at long last is in the process of being
officially recognized as ‘essential'. Boron's role regarding bone health
appears to be mediated by its ability to reduce the urinary excretion
of calcium and magnesium, thus enhancing vitamin D as well (which is
directly interdependent with calcium). Boron's mechanism of action takes
place in the kidney. In a clinical study among 12 post-menopausal women
not on estrogen replacement therapy, boron was not only shown to
significantly diminish urinary losses of calcium and magnesium, but it
also raised levels of plasma ionized calcium, beta-estradiol, and
testosterone.
Finally, Bone Basics contains 1000 IU of Vitamin D3
(Cholecalciferol) per daily dose; this is more than double the amount
of this essential vitamin than included in the original Calcium Magnesium Plus® formula. Bone Basics has been formulated based on the
latest research in the field. The innovative combination of ingredients
in Bone Basics makes it a complete formula for the support and
maintenance of optimal bone health.
Bone Basics est une formule contenant plusieurs nutriments conçue pour favoriser la santé osseuse. Bone Basics contient un
extrait lyophilisé d’os bovin qui est issu de bétail fermier australien
broutant dans les pâturages et non soumis aux antibiotiques de routine
ou aux hormones de croissance rBGH. La consommation du calcium, lorsque
combinée avec une consommation de la vitamine D suffisante, une
alimentation saine et des exercices réguliers, peut réduire la risque du
développement de l’ostéoporose.
AORTM certifie qu'aucun ingrédient ne
figurant pas sur l'étiquette n'a été ajouté au produit. Ce dernier ne
contient pas de blé, de gluten, de noix, de produits laitiers ou d'œufs.
Pososlogie Adulte:
Prendre jusqu’à six capsules par jour avec repas, ou selon les recommandations d’un professionnel de la santé.
Mise en Garde:
Consultez un professionnel de la
santé avant d'en faire l'usage si vous si prenez des médicaments
anticoagulants ou lorsqu'un cancer dépendant d’œstrogène existe.
Consultez un professionnel de la santé si les symptômes s'aggravent.
Applications: Santé osseuse, Excellent source de calcium et de nutriments bénéfiques pour les os
Grossesse/Allaitement:
Consultez un professionnel de la santé avant d'en faire l'usage
Source: CHO - extrait lyophilisé d'os de bovin
Australien. Recueilli des vaches élevées en pâturage et qui ne sont pas
traité avec antibiotiques ou des hormones. Aucun rBGH. Nous garantissons
que ce produit ne contient aucune trace d'encéphalopathie spongiforme
bovine.
Le squelette humain se compose de 206 os et même un régime
alimentaire sain ne peut pas toujours fournir les quantités de calcium,
de vitamine D et d'autres aliments essentiels exigés pour soutenir leur
santé optimale.
Le complexe microcristallin d'hydroxyapatite
osséine (CMHO) est un extrait lyophilisé d'os bovin qui aide à maintenir
la structure microcristalline osseuse intacte. Le CMHO est une source
riche de micronutriments contenus dans tous les os et est une source
nutritive à spectre complet. Plus de 30 ans d'épreuves cliniques ont
démontré que le CMHO contient une source unique de calcium qui est la
meilleure source de calcium pour le support et le maintien de la santé
osseuse. En outre, le MCHC est riche en phosphore, un element qui
compose plus de la moitié de la teneur en minéraux de l'os et qui est
nécessaire au fonctionnement des ostéoblastes - les cellules
responsables de la création de nouveaux os.
Le MCHC contenu dans la formula Bone Basics provient
de l'Australie et de la Nouvelle Zélande où les animaux ne sont pas
soumis aux traitements d'antibiotiques et d'hormones de croissance
recombinantes bovines et où aucun cas d'encéphalopathie spongiforme
(maladie de la vache folle) n'a été relevé.
Bone Basics
contient également du magnésium, un minerai essentiel pour
l'infrastructure osseuse, tout comme le phosphore et le calcium. Le
bore, la glucosamine, les vitamines K2 et D3, aussi bien que le zinc, le
cuivre, et le manganèse sont également inclus dans cette formule
optimale pour le maintien de la santé des os.