AOR, Arginine, 180 vcaps
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Arginine - 180 vcaps, aor vitamins supplements
AOR, Arginine, 180 vcaps is manufactured by AOR Supplements
- Improves heart health
- Nitric oxide precursor
- Protects the heart from high blood sugar levels
- Helps in cellular energy production
Arginine is L-arginine, a conditionally essential
amino acid and the main precursor in the body in the synthesis of nitric
oxide (NO), now accepted to be the "endothelium-derived relaxation
factor (EDRF)." L-arginine helps to improve exercise capacity.
|Serving Size: 1 Capsule
|Amount Per Serving
|Non-medicinal ingredients: microcrystalline cellulose. Capsule: hypromellose.
that no ingredients not listed on the label have been added to the
product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish,
shellfish or any animal byproduct.
Adult Dosage: Take 3 capsules one to three times daily on an empty stomach, or as directed by a qualified health practitioner.
Do not use if you have had a myocardial infarction (heart attack).Do
not use if you have asthma. Consult a health care practitioner prior to
use if you are taking cardiovascular medications, potassium-increasing
drugs or sildenafil.
Pregnancy/Nursing: Do not take.
- Supports exercise capacity
- Nitric oxide production
amino acid Arginine was first characterized in 1886 by the Swiss
Chemist Ernst Schulze. Little research was conducted subsequently,
however, since there was widespread belief that adequate amounts of
arginine could be synthesized in the body, which undoubtedly delayed
further research. In the 1930′s, research showed that arginine
deprivation decreased the rate of growth and/or led to severe metabolic
disorders and even death.
the last forty years, numerous studies have emphasized the diverse
range of arginine’s physiological effects including release of growth
hormone, glucagon and insulin, amino acid detoxification and for the
synthesis of creatine – an important compound for generating ATP, or
“cellular currency.” Arginine is a physiological precursor of nitric
oxide, a potent vasodilator. In the mid 80′s the importance of nitric
oxide (NO) as a ubiquitous signaling molecule was highlighted, which
helped explain arginine’s diverse effects.
Arginine is beneficial
for improving the function of the cardiovascular system due to its
antiatherogenic, antiischaemic and antithrombic properties, all of
which help to prevent the formation of plaque in the arteries. In
diabetes it is also used for reversing the effects if high vascular
glucose concentration. Studies also demonstrate the benefits of arginine
for treating male infertility, interstitial cystitis and liver and
studies have demonstrated arginine’s antiatherogenic, antiischaemic and
antithrombic properties, without which the eventual consequence is
formation of plaque in the arteries, which leads to compromised
endothelial function which in turn leads to reduced vasodilation.
Arginine has been shown to not only prevent further progression but also
even to promote the regression of plaque formation! An interesting
study by Boger and colleagues compared the effects of a standard
cholesterol drug called lovastatin (Mevacor) with the effects of
arginine in cholesterol-fed rabbits. Lovastatin reduced cholesterol by
32%, but had only a weak effect on the formation of plaque.
Interestingly, arginine had no effect on cholesterol yet completely
blocked the formation of plaque.
initiating event in atherosclerotic plaque formation is monocyte
adhesion to the endothelium followed by entry of these monocytces into
the subintimal layer of the blood vessels, their transformation into
macrophage cells followed by their uptake of lipids and eventually fatty
streak/foam cell formation. Arginine is reported to reduce the adhesion
of monocytes to the endothelial cells in coronary patients and in
smokers. Another mechanism through which arginine may be acting is that
NO has potent free radical quenching properties and hence acts as an
Numerous experimental and clinical studies have
demonstrated the therapeutic potential of high dose arginine for the
prevention and treatment of a broad spectrum of cardiovascular diseases,
in preventing endothelial damage and in the restoration of endothelial
function including arterial hypertension, peripheral vascular disease,
angina and the metabolic syndrome. Arginine has been successfully used
for the treatment of mild to moderate congestive heart failure, with a
dose of 12.6g per day demonstrating a beneficial effect.
mellitus is a metabolic disorder which strongly predisposes an
individual to cardiovascular disease. Hyperglycemia is thought to cause
diabetic complication via the following mechanism: formation of reactive
oxygen species (ROS), which cause direct endothelial damage; and
increased formation of advanced glycation end-products (AGEs) which are
toxic species that alter the structure and function of physiological
proteins. The net result is an increase in retinopathy, nephropathy and
neuropathy. High blood glucose levels also reduce NO availability.
Arginine, however, can reverse the vascular effects of high glucose
concentration. A small randomized, double blind, placebo-controlled
study demonstrated that 6 grams of arginine improved exercise capacity
in angina patients.
Arginine reduces platelet aggregation and
blood viscosity, improves blood flow and helps repair vascular injury.
Arginine is considered a promising therapeutic agent for the prevention
of restenosis and improving the outcome following heart transplantation
and coronary bypass.
a. Interstitial cystitis
A dose of 1.5g daily for 6 months in a clinical trial resulted in a
significant decrease in urinary voiding discomfort and diminished
abdominal and vaginal/urethral pain. Urinary frequency was significantly
been used for treating male infertility by improving spermatogenesis.
Since arginine is a precursor of NO, and NO is a potent vasodilator, it
is conceivable that arginine would be of benefit in erectile dysfunction
much like the mechanism of action of Viagra.
c. Liver and brain injury
Animal studies have reported benefits in acute liver and brain injuries.
is most commonly used to enhance exercise capacity, to improve nitric
oxide production, in cardiovascular disorders and for erectile
AOR offers a high quality arginine supplement to enhance cardiovascular and overall health.
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