AOR, Advanced Bone Protection, 30 vcaps
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Advanced Bone Protection - Osteo Bone Protection - 30 vcaps, aor vitamins supplements
AOR, Advanced Bone Protection, 30 vcaps is manufactured by AOR Supplements
Advanced Bone Protection
- Reduces bone loss
- Improves bone strength
- Stimulates bone building cells
- Supports collagen production
Advanced Bone Protection contains MBP, an active
protein complex from the whey fraction of milk. Research suggests that
MBP can positively impact bone health by reducing bone loss (resorption)
and increasing bone mineral density.
|Serving Size: 1 Capsule
|MBP† (A specific basic protein fraction derived from milk)
is owned by Snow Brand Milk Products Co., Ltd. Non-medicinal
ingredients: microcrystalline cellulose. Capsule: hypromellose, water.
that no ingredients not listed on the label have been added to the
product. Contains no wheat, gluten, corn, nuts, soy, eggs, fish or
Adult Dosage: Take 1 capsule daily or as directed by a qualified health care practitioner.
Cautions: Advanced Bone Protection is not recommended for people with milk allergies.
- Bone health
- Women's health
What Is Advanced Bone ProtectionTM ?
in general (and bovine milk in particular) arguably contains more
growth factors than any other single food source. Growth factors are
specific proteins which act as intracellular signaling molecules.
Scientists in Japan have isolated a fraction from whey protein which
they have determined to have positive metabolic effects on bone health.
It is called Milk Basic Protein, or MBP®, and it is the active
ingredient in Advanced Bone Protection from AORTM.
How Does Advanced Bone ProtectionTM Work ?
very briefly, MBP stimulates the activity and proliferation of
osteoblasts (bone-building cells) while simultaneously suppressing the
activity and proliferation of osteoclasts (cells responsible for the
resorption – or breakdown – of bone). MBP is particularly effective at
supporting the production of collagen as well as the retention of
calcium (see below).
first glance, the mechanism of action through which MBP exerts its
effects seems remarkably similar to that of its bone-enhancing nutrient
predecessors such as calcium, vitamin D and strontium. For example, MBP
assists in the absorption and retention of calcium, just as vitamin D
does. Unlike vitamin D, however, MBP does so via the inhibition of
cystein protease due to the presence of the protein strain known as
cystatin C, which is part of the structure of MBP itself. Cystatin C
also inhibits the release of calcium from bones stimulated by thrombin,
interleukin-1 and prostaglandin E2. The essential nature of this
function cannot be understated, as calcium can metaphorically be
referred to as the mortar for the infrastructure that is collagen –
together contributing to form the complex that is bone.
protease also digests collagen in the bone matrix, further testimony to
the benefit of its inhibitory effect from the cystatin C contained in
MBP. MBP cultivates both the proliferation and activity of the
bone-building osteoblasts while conversely bridling the same
proliferation and activity among the osteoclasts responsible for the
resorption (breakdown) of older bone tissue. Even more revealing is the
extent of MBP’s inhibition of osteoclasts, suppressing the activity of
even the most isolated osteoclast cells. The association between the
osteoblast/osteoclast relationship and collagen lies in the ability of
osteoblasts to produce collagen, and it is here where MBP comes into its
own. The ability to specifically manipulate osteoblasts into producing
more collagen in a manner that is more pronounced than that of its
osteo-nutrient predecessors is an additional factor that makes MBP
unique. Furthermore, MBP also increases serum concentrations of
osteocalcin (BGP, also called Gla protein), which is the major
non-collagenous protein in bone.
Science In Action: What The Studies Say
As with all promising nutraceutical innovations, early in-vitro
research revealed encouraging indications of what would later become
identified as MBP. Indeed, such indications at the in-vitro level need
to be encouraging in order to secure further, in-vivo studies. This
preliminary research identified whey protein as having an exemplary
influence on the relationship between osteoblasts and osteoclasts. It
was discovered that in addition to fortifying osteoblasts, whey protein
was also shown to suppress osteoclast-mediated bone resorption and
osteoclast cell formation. This began a lengthy scientific process to
isolate the fraction of whey protein that scientists believed was
responsible for these bone-reinforcing effects. MBP was the eventual
result of that process.
recent scientific isolation and practical procurement of MBP has lead
to numerous studies with excitingly impressive results. The first study
among humans involved thirty-three healthy women who were randomly
assigned to treatment with either a placebo or MBP (40 mg per day) for
six months. The bone mineral density (BMD) of the left heel bone of each
subject was measured at the beginning of the study and at the end.
Serum and urine indices of bone metabolism were measured at the base
line, three month intervals, and again at the end of the study. When
standard BMD testing was conducted at the end of the study, the women in
the MBP group gained approximately 70% more bone mineral density than
the control group. Furthermore, urinary markers of bone loss – in this
case, cross-linked type- I collagen/creatinine and
deoxypyridinoline/creatinine, were ‘significantly decreased’ in the MBP
A study among healthy adult men was similarly impressive,
as well as another study among healthy adult women in 2002. This
particular double-blind, placebo-controlled trial measured radial bone
mineral density, and once again the mean BMD value of the MBP group was
‘significantly higher’ than that of the placebo group.
A Summary of the Results of MBP Studies:
• In a study among healthy menopausal women, the MBP group reported a
bone mineral density (BMD) increase of 1.21% while the placebo group
recorded a 0.66% BMD decrease.
• In another study among healthy
adult women, the MBP group gained approximately 70% more bone mineral
density than the control group.
• MBP reduced the number of pits on the bone surface caused by bone resorption by approximately 85% in an in-vitro study.
• In yet another study among healthy adult females, the MBP group
displayed a 3% increase in the BMD of the radius (a forearm bone near
the wrist) compared to a 1.3% BMD decrease in the placebo group.
Finally, the MBP in Advanced Bone ProtectionTM
from AOR comes in small, convenient capsules that can be taken with or
without food and have no interactions with calcium or any other
who are wishing to improve their bone health will significantly benefit
from using bone supporting products such as vitamins and mineral,
lactoferrin and milk basic protein.
Bone Protection works on several mechanisms: first, by reducing the
activity of bone destroying cells called osteoclasts; second, by
stimulating the activity of bone forming cells called osteoblasts;
third, by increasing the amount of collagen produced by the osteoblasts
and laid down in the bone; and finally, by improving the utilization of
calcium ions into the bone. The last mechanism makes Advanced Bone
Protection unique in its action by virtually “catching” as many calcium
ions as possible thereby preventing the deposition of calcium in other
tissues like the arteries, kidneys and others. Advanced Bone Protection
concentrates in the bone and acts like Velcro and thus picks up calcium
ions which can’t help but “stick” to the bone which is where they are
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