AOR guarantees that no ingredients not listed on the label have been added to Advanced Bone Protection. AOR Advanced Bone Protection contains no wheat, gluten, corn, nuts, soy, eggs, fish or shellfish.

Suggested Use
Take one capsule daily with/without food or as directed by a qualified health care practitioner.

Main Applications of Advanced Bone Protection
* Supports skeletal health

Source
Bovine Milk.

Pregnancy / Nursing
Safe.

Cautions
Advanced Bone Protection is not recommended for people with milk allergies.

At first glance, the mechanism of action through which Milk Basic Protein exerts its effects seems remarkably similar to that of its bone-enhancing nutrient predecessors such as calcium, vitamin D and strontium. For example, MBP assists in the absorption and retention of calcium, just as vitamin D does. Unlike vitamin D, however, MBP does so via the inhibition of cystein protease due to the presence of the protein strain known as cystatin C, which is part of the structure of MBP - Milk Basic Protein itself. Cystatin C also inhibits the release of calcium from bones stimulated by thrombin, interleukin-1 and prostaglandin E2. The essential nature of this function cannot be understated, as calcium can metaphorically be referred to as the mortar for the infrastructure that is collagen - together contributing to form the complex that is bone.

Cystein protease also digests collagen in the bone matrix, further testimony to the benefit of its inhibitory effect from the cystatin C contained in MBP. Milk Basic Protein cultivates both the proliferation and activity of the bone-building osteoblasts while conversely bridling the same proliferation and activity among the osteoclasts responsible for the resorption (breakdown) of older bone tissue. Even more revealing is the extent of MBP's inhibition of osteoclasts, suppressing the activity of even the most isolated osteoclast cells. The association between the osteoblast/osteoclast relationship and collagen lies in the ability of osteoblasts to produce collagen, and it is here where MBP comes into its own. The ability to specifically manipulate osteoblasts into producing more collagen in a manner that is more pronounced than that of its osteo-nutrient predecessors is an additional factor that makes MBP unique. Furthermore, Milk Basic Protein also increases serum concentrations of osteocalcin (BGP, also called Gla protein), which is the major non-collagenous protein in bone. 

A Summary of the Results of Milk Basic Protein Studies:
• In a study among healthy menopausal women, the MBP group reported a bone mineral density (BMD) increase of 1.21% while the placebo group recorded a 0.66% BMD decrease.
• In another study among healthy adult women, the MBP group gained approximately 70% more bone mineral density than the control group.
• MBP reduced the number of pits on the bone surface caused by bone resorption by approximately 85% in an in-vitro study.
• In yet another study among healthy adult females, the MBP group displayed a 3% increase in the BMD of the radius (a forearm bone near the wrist) compared to a 1.3% BMD decrease in the placebo group.

Finally, the MBP in AOR Advanced Bone Protection comes in small, convenient capsules that can be taken with or without food and have no interactions with calcium or any other nutrients.