AOR, Boswellia, 90 vcaps
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Boswellia Nanovailable - 90 lcaps, aor vitamins supplements
AOR, Boswellia, 90 vcaps is manufactured by AOR Supplements
- Reduces pain and inflammation
- Shown to significantly improve osteoarthritis symptoms when used for at least 1 month
- Dissolved in self-emulsifying formula to enhance absorption
AOR's nanoVAILABLE Boswellia is standardized Boswellia serrata extract,
a botanical used in Ayurvedic medicine for support in inflammatory
conditions. Boswellia is standardized for boswellic acids, key
triterpene phytonutrients, and this standardized extract has been
clinically demonstrated to help relieve pain and swelling associated
with osteoarthritis of the knee. AOR’s nanoVAILABLE Boswellia is
formulated with solubilized B. serrata extract in a self-emulsifying formula to maximize bioavailability.
||90 Liquid Caps
|Serving Size: 1 Capsule
|Amount Per Serving
|Boswellia serrata (Boswellic Acids 40%)
|Non-medicinal ingredients: potato starch, medium chain triglycerides, polysorbate 20. Capsule: hypromellose, gellan gum, water.
that no ingredients not listed on the label have been added to the
product. Contains no wheat, gluten, nuts, dairy, soy, eggs, fish,
shellfish, or any animal byproduct.
Adult Dosage: Take 1 capsule three times a day with food, or as directed by a qualified health care practitioner.
Some people may experience mild gastrointestinal effects such as
diarrhea, abdominal pain/cramps and nausea. Hypersensitivity (e.g.
allergy) has been known to occur; in which case, discontinue use.
Pregnancy/Nursing: Consult a health care practitioner before use
Boswellia serrata extract
- Skin disorders
- Inflammatory bowel disease
goal of AOR, since its inception, has been to provide our customers
with the most advanced, science-backed products available. The problem
that has plagued many dietary supplements, as well as the pharmaceutical
industry, is the amount of each compound that actually makes it into
the bloodstream. This is referred to as ‘bioavailability’. Over the
years, many ingredients have shown incredibly promising results in early
stages, when studied in vitro, with cultured cells showing remarkable
transformations at the hand of many natural products. When taken by
humans, however, these effects are often significantly decreased, or
completely absent. The root of this problem is bioavailability. The
nanoVAILABLE line from AOR takes on this problem of bioavailability,
offering products with improved bioavailability through advanced
Ayurvedic Boswellia serrata
are many medicinal plants of great therapeutic value referred to in the
ancient treatment system of Ayurveda. One particular plant of much
repute is resin of the tree Boswellia serrata, or Frankincense, which the Ayurved materia medica claimed to have potent anti-inflammatory and anti-arthritic properties.
like many herbal extracts, suffers from poor bioavailability due to
poor solubility and absorption. Traditionally, up to 3 grams needs to be
consumed in order to achieve any therapeutic benefit. In order to
increase bioavailability, that is, to achieve greater benefits from less
material, nanoVAILABLE Boswellia has been dissolved in oil, giving the
smallest particles possible, and then combined with ingredients to
promote the formation of an emulsion, so that the oil can be dissolved
and absorbed more easily in the body.
As Good or Better than NSAIDs for Arthritis?
mechanism of action of boswellic acids is similar to the action of
NSAIDs. Prostaglandins and leukotrienes are two classes of arachidonic
acid-derived mediators of inflammation. Leukotrienes, for which
5-lipooxygenase (5-LOx) is the key enzyme in synthesis, are considered
to be involved in the initiation and maintenance of various inflammatory
diseases, for example arthritis, Crohn’s disease, ulcerative colitis,
asthma etc. Boswellic acids are potent inhibitors of 5-lipooxygenase
product, including 5-hydroxyeiconatetraenoic acid (5HETE), and
leukotriene B4 (LTB4), which cause: bronchoconstriction, chemotaxis, and
increased vascular permeability. Other anti-inflammatory plant
constituents, such as quercetin, also block this enzyme, but they do so
in a more general fashion, as an antioxidant, whereas Boswellia seems to
be a specific inhibitor of 5-LOx.
It is known that non-steroidal
anti-inflammatory drugs can cause a disruption of glycosaminoglycan
(GAG) synthesis that can accelerate the articular damage in arthritic
Boswellic acids have also been shown to decrease the
prevalence of matrix metalloproteinases in the synovial fluid. These
enzymes are often over expressed in osteoarthritis patients, and have
been implicated in the degredation of cartilage in the joints.
Other biological activities
has also been observed to inhibit human leukocyte elastase (HLE), which
may be involved in the pathogenesis of emphysema. HLE also stimulates
mucus secretion and thus may play a role in cystic fibrosis, chronic
bronchitis, and acute respiratory distress syndrome. Other uses may
include asthma, skin conditions, and ulcerative colitis.
extracts of the resin demonstrated reduced carrageenan-induced paw
edema in normal rats and mice as well as in adrenalectomized rats.
Further, extracts showed anti-arthritic activity in formaldehyde and
adjuvant-induced arthritis in rats and BSA-induced arthritis in the
rabbit. In addition, the researchers found the above extract to be more
beneficial, less toxic and more potent than the standard drug of choice,
Ketoprofen, a widely used prescriptive Non-Steroidal Anti-inflammatory
Drug (NSAID). More recently, a number of researchers have identified the
anti-inflammatory activity of the ethanolic extracts of the resin to be
due to boswellic acids, in particular the alpha and beta isomers.
Recently, a more purified compound standardized for 40% boswellic acids
and 65% organic acids has shown potent anti-inflammatory and
anti-arthritic activity without any of the adverse effects (e.g.
gastro-intestinal, CNS and cardiovascular).
A study including 70 patients suffering from osteoarthritis of the knee
has demonstrated the positive effects of boswellic acids in humans.
These patients received either 100mg or 250mg of boswellic acid
containing extract, or a placebo, daily for 90 days. Patients receiving
either dose of boswellic acids demonstrated significant improvements in
both pain and functional ability of the knee joint. Even more impressive
is that patients receiving the 250mg dose showed these improvements as
early as 7 days following the start of treatment and required other pain
medication 72% less often than patients taking placebos.
Boswellia vs. NSAIDs
recent in-vivo study examined Boswellia and ketoprofen for their
effects on glycosaminoglycan metabolism. Boswellia significantly reduced
the degeneration of GAGs compared to controls, whereas ketoprofen
caused a reduction in total tissue GAG content.
Boswellia also demonstrated a marked inhibitory effect on both the classical and alternate complement systems.
investigation of Boswellia’s analgesic and psychopharmacologic effects
noted that it “was found to exhibit marked sedative and analgesic
effects” in animals.
are suggested to play a role in the inflammatory process of ulcerative
colitis (UC). Boswellia 350mg three times a day was comparable to
sulfasalazine (at 1g three times a day), a standard prescriptive drug in
ulcerative colitis (UC).
is not a very well-known herb, although its popularity is increasing.
Boswellia may be one of nature’s most powerful anti-inflammatories,
although clinical results may be inconsistent due to its poor
for a Boswellia extract standardized for 40% boswellic acids. Any
product claiming to contain 65% boswellic acids probably contains 65%
organic acids, of which 40% or less are boswellic acids. Older, less
specific assay techniques do not distinguish the boswellic acid content
from the organic acids.
more out of Boswellia with AOR’s nanoVAILABLE technology, making it
more absorbable and more effective that regular extracts. AOR’s
nanoVAILABLE Boswellia is a standardized extract providing 65% organic
acids, of which a minimum of 40% are boswellic acids.
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